Targeting Cancer Pathways with Achyranthes aspera: A Computational and Experimental Approach Leveraging its Urinary Tract Infection-Fighting Properties

Abstract

Urinary tract infections (UTIs) are among the most common bacterial infections, particularly in women because of anatomical and physiological factors. As antibiotic-resistant bacteria become more prevalent, the search for natural alternatives to standard medications is increasingly essential. The study focuses on the antibacterial potential and phytochemical assets of Achyranthes aspera against the UTI Infectious Bacteria, such as K. pneumoniae. The Achyranthes aspera plant was extracted in methanol, and antibacterial activity was carried out by using the agar well diffusion method and minimal inhibitory concentration and minimal bactericidal concentration. The inhibition proved that plants was capable of inhibiting bacterial growth. Phytochemical screening confirmed the presence confirmed the presence of bioactive constituents including alkaloids flavonoids, phenols, tannins, terpenoids, saponins. Steroids. The plant extract was poteny against biofilm formation in tested pathogen. This study emphasizes the potential of achyranthes aspera in being a natural antimicrobial agents for the control of UTIs. Its strong antibacterial activity and its phytochemical content together with its use in the traditional herbal medicine