1/2026 vol. 6

Pages 1-430 (January 2026)

COVER IMAGE

Cover Image: Volume 6, Issue 1

NRFHH 2026;6(1):1

DOI: https://doi.org/10.53365/nrfhh/217652

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ISSUE INFORMATION

Issue Information

NRFHH 2026;6(1):2-10

DOI: https://doi.org/10.53365/nrfhh/217653

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ORIGINAL RESEARCH PAPER

Unraveling the Biosynthetic Gene Clusters and In Silico Insights into Meroterpenoids from the Indonesian Marine Sponge Endosymbiont Fungus Aspergillus nidulans

Erlidawati Erlidawati Erlidawati, Chessy Rima Mustika, Musri Musman, Diah Astika Winahyu, Viqqi Kurnianda

NRFHH 2026;6(1):11-23

DOI: https://doi.org/10.53365/nrfhh/206017

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ORIGINAL RESEARCH PAPER

The Impact of Lactobacillus casei in Soy Yogurt for Healthy Aging

Lindawati Valentina Legowo, Teresa Liliana Wargasetia, Fanny Rahardja

NRFHH 2026;6(1):24-31

DOI: https://doi.org/10.53365/nrfhh/211520

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REVIEW PAPER

A Comprehensive Review on Essential Oil Composition and Gastric Effect of Minthostachys mollis: An Ethnomedicinal Resource from Andes

Frank Romel León-Vargas, Ricardo Diego D.G. de Albuquerque, Zsanett Hajdu, Daniel D. Carrasco-Montañez, Yessenia V.S. Ramos-Rivas, Denilson M. Del Castillo-Mozombite, Matsen R. García-Navarro

NRFHH 2026;6(1):32-39

DOI: https://doi.org/10.53365/nrfhh/210623

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ORIGINAL RESEARCH PAPER

Characterization, molecular docking, and therapeutic properties of biomaterial obtained from Pangasianodon hypopthalmus

Gomathy Meganathan, Manikantan Pappuswamy

NRFHH 2026;6(1):40-56

DOI: https://doi.org/10.53365/nrfhh/210624

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ORIGINAL RESEARCH PAPER

Efficacy of JaminTea Herbal Mouthwash Against Streptococcus mutans, Porphyromonas gingivalis, and Candida albicans

Vinna Kurniawati Sugiaman, Sijani Prahastuti, Jeffrey Jeffrey, Wahyu Widowati, Vini Ayuni, Dhanar Septyawan Hadiprasetyo

NRFHH 2026;6(1):57-68

DOI: https://doi.org/10.53365/nrfhh/211488

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ORIGINAL RESEARCH PAPER

Evaluation of Anti-arthritic Activity of ArthoCan – V50 Tablets using CFA induced Rheumatoid Arthritis in Wistar rats

Swagata Tavhare, Smita Jadhav, Vaishali Undale, Sarang Deshpande, Vini Mehta

NRFHH 2026;6(1):69-87

DOI: https://doi.org/10.53365/nrfhh/210627

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ORIGINAL RESEARCH PAPER

Chemical Composition and Bioactivities of Pomelo (Citrus maxima) Peel Essential Oil

Pham My Hao, Le Pham Tan Quoc

NRFHH 2026;6(1):88-94

DOI: https://doi.org/10.53365/nrfhh/210631

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ORIGINAL RESEARCH PAPER

Mineral Composition and Health Risk Assessment of Winter-Grown Vegetables from West Bengal, India

Tushar Adhikari, Atithi Majumdar, Prerona Saha

NRFHH 2026;6(1):95-105

DOI: https://doi.org/10.53365/nrfhh/211521

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ORIGINAL RESEARCH PAPER

Pharmcognostical Standardization, Antioxidant, and in Vivo Dermal Toxicity Studies of Polyherbal Extract

Preeti Sharma, Shikhar Verma

NRFHH 2026;6(1):106-120

DOI: https://doi.org/10.53365/nrfhh/210626

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ORIGINAL RESEARCH PAPER

Investigating the Potential of Sivanarvembu Kuzhi Thailam, A Classical Siddha Formulation Against Psoriasis: GC-MS Analysis and Molecular Docking Studies

Gayathri Gunalan, Rathinamala R, Rajalakshmi Kumar

NRFHH 2026;6(1):121-135

DOI: https://doi.org/10.53365/nrfhh/210636

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ORIGINAL RESEARCH PAPER

Effect of Multiple Mutation in PZase From Clinical Isolate of Pyrazinamide-Resistant Mycobacterium tuberculosis on Its activity and structure

Purkan Purkan, Raden Estiawan, Imam Siswanto, Sofijan Hadi, Sri Sumarsih, Muhammad Ikhlas Abdjan, Merlyn Sujatha Rajakumar

NRFHH 2026;6(1):136-146

DOI: https://doi.org/10.53365/nrfhh/210632

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ORIGINAL RESEARCH PAPER

Blumea balsamifera Extract Induces Apoptosis and Cell Cycle Arrest in T47D Cell Line

Fairuz Sarah Kamila, Nuraini Rosyadah, Muhammad Hermawan Widyananda, Feri Eko Hermanto, Mufidah Afiyanti, Dinia Rizqi Dwijayanti, Nashi Widodo

NRFHH 2026;6(1):147-159

DOI: https://doi.org/10.53365/nrfhh/210625

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ORIGINAL RESEARCH PAPER

Exploring Pigeon Pea (Cajanus cajan) as a Functional Food: Nutritional Profile, Bioactive Compounds, and Enzyme Inhibition for Glycemic Control

Elly Purwanti, Feri Eko Hermanto, Farida Rachmawati, Aso Hameed Hasan, Moh Mirza Nuryady, Tutut Indria Permana, Wahyu Prihanta

NRFHH 2026;6(1):160-178

DOI: https://doi.org/10.53365/nrfhh/210629

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REVIEW PAPER

Advancing Traditional Medicine in India: Academic, Research, and Regulatory Perspectives on Ayush Systems

Ghazala Javed, Shree Devi M.S., Somenath Roy Chowdhury

NRFHH 2026;6(1):179-189

DOI: https://doi.org/10.53365/nrfhh/210628

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REVIEW PAPER

Unripe Fruits Found as Sources of Bioactive Compounds: A New Frontier in Drug Discovery

Amitesh Chakraborty, Santanu Giri, Shubhadeep Hazra, Aniruddha Sarkar, Parnasree Chakraborty, Tushar Adhikari

NRFHH 2026;6(1):190-210

DOI: https://doi.org/10.53365/nrfhh/209465

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ORIGINAL RESEARCH PAPER

Exploring the Potential of Red Fruit Oil to Modulate Melanogenesis by Evaluating MITF Gene Expression in α-MSH-Induced B16F10 Melanoma Cells

Sri Trisnawaty, Julia Windi Gunadi, Hana Ratnawati

NRFHH 2026;6(1):211-220

DOI: https://doi.org/10.53365/nrfhh/211494

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REVIEW PAPER

Application of CRISPR/Cas9 in Reconstructing Bacterial Deoxyribonucleic Acid for the Production of Biologically Active Compounds

Chi Linh Tran, Khanh Dung Nguyen

NRFHH 2026;6(1):221-234

DOI: https://doi.org/10.53365/nrfhh/213301

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REVIEW PAPER

Antibiotic resistance and herbal alternatives in endodontics: mechanisms, evidence, and clinical outcomes

Mohmed Isaqali Karobari

NRFHH 2026;6(1):235-248

DOI: https://doi.org/10.53365/nrfhh/213756

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ORIGINAL RESEARCH PAPER

A clinical evaluation of liposomal (Lipomac™) versus nonliposomal vitamin C: A randomized, open-label, cross-over trial in healthy subjects

Sravani Thimmannagari, Shivaprasad HN, Arnab Chatterjee, Madhu Krishnamani, Gaurav Soni, Divanji Manohar

NRFHH 2026;6(1):249-256

DOI: https://doi.org/10.53365/nrfhh/211489

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ORIGINAL RESEARCH PAPER

Computational identification of hub genes and bioactive compounds in breast cancer via meta-analysis of transcriptomic data, network pharmacology, molecular docking, and ADMET evaluation

Fen Tih, Raffael L. D. Simanjuntak, Ardo Sanjaya

NRFHH 2026;6(1):257-268

DOI: https://doi.org/10.53365/nrfhh/210633

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ORIGINAL RESEARCH PAPER

An Ethnopharmacological Survey and Antioxidant Properties of Medicinal Plants Used to Treat Cutaneous Leishmaniasis in Central Morocco: Health Professionals’ Knowledge of Local Community Use

Mohammed-yassine Takzima, Mohamed Echchakery, Mohamed Hafidi, Loubna El Fels

NRFHH 2026;6(1):269-279

DOI: https://doi.org/10.53365/nrfhh/211490

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ORIGINAL RESEARCH PAPER

Calamondin (Citrus microcarpa) Peel Essential Oil: Physicochemical, Chemical, and Biological Properties

Nguyen Ngoc Thuan, Le Pham Tan Quoc, Lam Bach Bao Phuong, Pham Thi Quyen

NRFHH 2026;6(1):280-286

DOI: https://doi.org/10.53365/nrfhh/211518

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ORIGINAL RESEARCH PAPER

Phytochemical and In Vivo Antinociceptive and Anti-Inflammatory Studies of Eleutherine palmifolia Ethanolic Extract

Nurul Ismira Kusumawardani, Siti Khadijah Nawir, Ummul Khaerah, Lia Hafiyani, Sulfahri Sulfahri, Anna Khuzaimah, Yulia Yusrini Djabir

NRFHH 2026;6(1):287-295

DOI: https://doi.org/10.53365/nrfhh/213302

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ORIGINAL RESEARCH PAPER

Serum Formulation Containing Salmon DNA and Various Plant Extracts as Antioxidant and Anti-aging on UV-Induced Human Skin Fibroblast Cells

Wahyu Widowati, Rita Tjokropranoto, Philips Onggowidjaja, Min Kyu Na, Dwi Nur Triharsiwi, Dhanar Septyawan Hadiprasetyo, Garry Alexandro, Rizal Azis, Kasim Sakran Abass, Herry S. Utomo

NRFHH 2026;6(1):296-308

DOI: https://doi.org/10.53365/nrfhh/213305

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ORIGINAL RESEARCH PAPER

Potency of Rambutan (Nephelium lappaceum L.) Peel Extract to Overcome Skin Aging

Diana Krisanti Jasaputra, Young Ho Kim, Teresa Liliana Wargasetia, Wahyu Widowati, Heddy Herdiman, Agnia Nursyifa Fitria Romdhon, Anindita Putri Distya

NRFHH 2026;6(1):309-323

DOI: https://doi.org/10.53365/nrfhh/213306

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ORIGINAL RESEARCH PAPER

Holothuria scabra Methanol Extract Induces Apoptosis Via Modulation of Bax/Bcl-2 in Breast Cancer Mice Model

Hana Ratnawati, Teresa Liliana Wargasetia, Ardo Sanjaya, Dhimas Pratama Rizki Syahputra, Jasmine Wijaya

NRFHH 2026;6(1):324-334

DOI: https://doi.org/10.53365/nrfhh/210648

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ORIGINAL RESEARCH PAPER

Phytochemical Profiling and Network Pharmacology-Based Evaluation of Aphrodisiac Potential of Mirabilis jalapa L. Root Extract

Taufeek ., Anuj Kumar Sharma, Poonam Bhardwaj, Preeti Bala Anand, Namrata Singh, Afsha Khan, Dinesh Kumar Yadav, Arti Sinoria

NRFHH 2026;6(1):335-349

DOI: https://doi.org/10.53365/nrfhh/211491

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ORIGINAL RESEARCH PAPER

Efficacy of Irimedadi Oil and Virgin Coconut Oil Pulling on Plaque-Induced Gingivitis: A Randomized Controlled Trial

Isha Inamdar, Anmol Mathur, Ladusingh Rajpurohit, Chaitanya Buddhikot, Ruchik Anerao, Ankita Mathur

NRFHH 2026;6(1):350-358

DOI: https://doi.org/10.53365/nrfhh/210635

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ORIGINAL RESEARCH PAPER

Nanosuspension-Loaded Oral Transmucosal Drug Delivery of Clotrimazole for Effective Management of Oral Candidiasis

Shivani Shrikant Kumbhare, More Mangesh Rajendra, S. A. Tamboli, Md. Javeed. Y. Manure, Shaeesta Khaleelahmed Bhavikatti, Mohmed Isaqali Karobari

NRFHH 2026;6(1):359-370

DOI: https://doi.org/10.53365/nrfhh/211493

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ORIGINAL RESEARCH PAPER

Gas Chromatography–Mass Spectrometry Profiling of Bioactive Compounds in Ginger and Lemongrass Essential Oils: Insights into Their Potential Medical Applications

Fatmi Nirmala Sari, Mohamed Saifulaman Mohamed Said, Norhashima Abd Rashid

NRFHH 2026;6(1):371-379

DOI: https://doi.org/10.53365/nrfhh/211492

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ORIGINAL RESEARCH PAPER

Physicochemical Characterization of Apis dorsata Binghami Honey from the Wallacean Zone of Indonesia: Insights into an Under-Researched Resource for Human Health

Mokosuli Yermia Semuel, Herry Sumampouw, Anita Tengker, Alva Supit

NRFHH 2026;6(1):380-388

DOI: https://doi.org/10.53365/nrfhh/211519

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ORIGINAL RESEARCH PAPER

Homeobox Regulation of Nanocurcumin Against Glioblastoma: In Vitro Analysis

Rizal Azis, Wahyu Widowati, Diki Diki, Deni Rahmat, Ahmad Faried, Dwi Nur Triharsiwi, Aris Muhamad Nurjamil, Deviana Lavender Suhanto, Dhanar Septyawan Hadiprasetyo, Kasim Sakran Abass

NRFHH 2026;6(1):389-402

DOI: https://doi.org/10.53365/nrfhh/210630

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ORIGINAL RESEARCH PAPER

Influence of Leaf Age, Fruit Color, and Extraction Methods on Phytochemical Profile and Bioactivity of Cashew Leaves

Netnapa Chana, Wipawee Boonsri, Sonchai Intachai, Wankuson Chanasit, Parichat Thepthong

NRFHH 2026;6(1):403-415

DOI: https://doi.org/10.53365/nrfhh/210634

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ORIGINAL RESEARCH PAPER

Assessment of the antifungal and probiotic properties of three Lactiplantibacillus plantarum strains

Chbihi Kaddouri Ahmed, Eloirdi Samia, Miyah Youssef, Benjelloun Mohammed, M’hamdi Zakya, El Feniche Mohammed, El Khayari Abdelmajid, Belhaj Abdelhaq

NRFHH 2026;6(1):416-430

DOI: https://doi.org/10.53365/nrfhh/213303

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